DTN 032: Human embryo models grown from stem cells

Plus: the universe may be a quantum computer, robot removes inoperable tumor and saves patient's life, an artificial brain, Lockheed Martin's streetwear moment, AI talks to whales, and more.

The Big Picture

“A research team headed by Prof. Jacob Hanna at the Weizmann Institute of Science has created complete models of human embryos from stem cells cultured in the lab—and managed to grow them outside the womb up to day 14. As reported today in Nature, these synthetic embryo models had all the structures and compartments characteristic of this stage, including the placenta, yolk sac, chorionic sac and other external tissues that ensure the models' dynamic and adequate growth. Cellular aggregates derived from human stem cells in previous studies could not be considered genuinely accurate human embryo models, because they lacked nearly all the defining hallmarks of a post-implantation embryo. In particular, they failed to contain several cell types that are essential to the embryo's development, such as those that form the placenta and the chorionic sac. In addition, they did not have the structural organization characteristic of the embryo and revealed no dynamic ability to progress to the next developmental stage.” (Nature)

“For this story, I read through every crash report Waymo and Cruise filed in California this year, as well as reports each company filed about the performance of their driverless vehicles (with no safety drivers) prior to 2023. In total, the two companies reported 102 crashes involving driverless vehicles. That may sound like a lot, but they happened over roughly 6 million miles of driving. That works out to one crash for every 60,000 miles, which is about five years of driving for a typical human motorist. These were overwhelmingly low-speed collisions that did not pose a serious safety risk. A large majority appeared to be the fault of the other driver. Human beings drive close to 100 million miles between fatal crashes, so it will take hundreds of millions of driverless miles for 100 percent certainty on this question. But the evidence for better-than-human performance is starting to pile up.” (Ars Technica)

“When generative AI products started rolling out to the general public last year, it kicked off a frenzy of excitement and fear. Several months later, the bloom is coming off the AI-generated rose. Recent reports suggest that consumers are starting to lose interest: The new AI-powered Bing search hasn’t made a dent in Google’s market share, ChatGPT is losing users for the first time, and the bots are still prone to basic errors that make them impossible to trust. In some cases, they may be even less accurate now than they were before. A recent Pew survey found that only 18 percent of US adults had ever used ChatGPT, and another said they’re becoming increasingly concerned about the use of AI. Is the party over for this party trick?” (Vox)

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