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- DTN 051: First AI Discovered Drug Reaches Phase II Clinical Trials
DTN 051: First AI Discovered Drug Reaches Phase II Clinical Trials
Plus: F-35A certified to carry nuclear bomb, Pentagon swears it's not investigating alien tech, MIT claims superconducting breakthrough, analyzing bloodstains in space, and more.
“We have some amazing founders in the Calibrate portfolio and some of them do a lot better than the others—not necessarily because they're smarter, just because they're much better storytellers. From my perspective, there are not enough deep tech founders who appreciate the power of storytelling."
The Big Picture
“Insilico Medicine, the Hong Kong and New York-based biotech startup that has raised over $400 million to connect biology, chemistry, and clinical trial analysis using next-generation AI systems, announced a new paper today that highlights the journey of what it claims is the first AI-generated and AI-discovered drug — which has now reached Phase II clinical trials.
The paper, in Nature Biotechnology, presents the entire journey of INS018_055, a drug candidate that was discovered using Insilico’s AI platform to treat idiopathic pulmonary fibrosis, a relatively rare but aggressive lung disease. The paper discloses the raw experimental data and the preclinical and clinical evaluation of the potentially first-in-class TNIK inhibitor discovered and designed through generative AI.” (VentureBeat)
Deep Tech News
Colossal Biosciences creates induced pluripotent stem cells from elephant skin cells
MIT Claims Superconducting Breakthrough Means Fusion Power Can Be Practical
NASA satellite, Russian spacecraft crossed within 65 ft (20M) of each other
Claude 3 Opus reinvented this quantum algorithm from scratch in just 2 prompts
JPEG of the Week
In contrast to the expansive field of man-made solar panels, the courtyard of this control center for one of Europe’s largest solar farms in Karapinar, Turkey, aims to bring a sense of human scale and nature to the landscape. Named Central Control Building, it is designed to monitor and control the expansive field of 3.2 million solar panels.
The plant is capable of providing 3 billion kWh of energy ouptut, makig it Turkey's largest single source of solar electricity. I tis expected to meet 2 million people's annual domestic requirements while reducing carbon eissions by 1.5M tons each year. The Karapinar solar project alone was responsible for a 20% inrease in the percentage of solar power stations in Turkey. (via DeZeen)
Peer Review
Funding x M&A
Multiverse raises $27M for quantum software targeting LLM leviathans
Satellite servicing tech startup, led by former head of Ukraine’s space agency, lands $4M
Artemis Fund has a fresh $36M to back diverse founders solving ‘big, hairy problems’
Rakuten Medical, a biotech company developing cell-targeting therapies, raised a $119M Series E
Zama, a startup building homomorphic encryption tech, raised a $73M Series A
Quantum infrastructure company Maybell Quantum raised a $25M Series A
Wobble Genomics, a startup providing a novel approach to RNA sequencing, raised an $11.8M round
Vescent, a startup building quantum hardware, raised a $5M seed round
Glacier, a startup building recycling robotics, raised a $7.7M round
Kurs Orbital, a startup building satellite servicing tech, raised a $4M seed round
Multiverse Computing, a startup building a quantum software platform, raised a $27M equity round
AI-powered robotics startup Rios Intelligent Machines raised a $13M Series B
Miscellanea
How long will advanced civilizations try to communicate with us? / NASA unveils design for message heading to Jupiter's moon Europa / Claude 3 catches researchers testing it / Controversial new theory of gravity rules out need for dark matter / Engineer bought prison laptop and 1,200 incarcerated folks lost their devices / The Obscene Energy Demands of A.I / CSI in space: Analyzing bloodstain patterns in microgravity / Pentagon says no evidence of secret US work on alien tech / Tesla’s Berlin factory to shut down for days after suspected arson attack cuts power / Binance made crypto perfume in a baffling attempt to woo women / Thieves using cellular and Wi-Fi jammers to enter homes for robbery
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